CBD Information and Frequently Asked Questions
Brief Glossery for CBD Oil & CBD Houston
CBD is the abbreviation for Cannabidiol
Carrier oil is an additive used to dilute essential oils and carry the essential oil onto the skin or for oral consumption.
Sublingual means taken orally, applied under the tongue.
Tincture is a liquid extract made from herbs that is taken orally.
Sublingual and tincture are often used interchangably.
About CBD Houston’s Products
Our CBD is sourced from American farms that we visit. The hybridized hemp we use are from seed stock that is approved and regulated by the department of agriculture of each state of origin. Additionally, all of our products contain less than .3% THC.
CBD For Pets
If your pet is dealing with arthritis, anxiety, seizures, pain, poor appetite, vomiting, or other chronic illnesses then Cannabidiol may be what you’re looking for. Always consult your veterinarian.
Scientific studies on the effectiveness of CBD for pets is relatively new – and still lacking. But open minded veterinarians and pet owners report their fair share of individual success stories all over the internet.
In a 2016 survey conducted by the American Holistic Veterinary Medical Association (AHVMA), 19.13% of respondents reported that the use of hemp products decreased seizures and convulsions in their dogs. Even more stunning 68.8% of respondents said they preferred using hemp products to conventional medicine. Read the full article, “Consumers’ Perceptions of Hemp Products for Animals” printed in JAHVMA Volume 42, Spring Issue, 2016.
Methods Utilized During Processing CBD Houston’s Products
Co2 Extraction or Ethanol Extraction
Dewaxed via Winterization
Short Path Distillation
find more information about these processes and why they’re important below
CBD Houston LLC uses flavoring from cold pressed organic essential oils or other natural or organic flavor sources. Similarly, our carrier oils are from organic and natural sources only.
Wholesale CBD and White Label CBD
We are a wholesale CBD company that primarily vends within the wellness community, where to buy CBD Houston. This ensures care and exceptional customer service. If you are interested in white label CBD (private label) or buying wholesale CBD, please contact us with information about your business.
What are Cannabinoids?
Cannabinoids are a group of closely related compounds that act on cannabinoid receptors in the body, unique to cannabis [or hemp]. The body creates compounds called endocannabinoids (endo – means self), while hemp produces phytocannabinoids (phyto – means plant).
In 2003 the US Federal Government obtained US Patent 6630507 titled “Cannabinoids as antioxidants and neuroprotectants.” The patent claims:
“Cannabinoids have been found to have antioxidant properties… useful in the treatment… of [a] wide variety of… diseases, such as… inflammatory and autoimmune diseases… [and] to have… application as neuroprotectants… in the treatment of neurodegenerative diseases.”
The endocannabinoid system is perhaps the most important physiologic system involved in establishing and maintaining human health. Although the endocannabinoid system affects a wide variety of biological processes, experts believe that its overall function is to regulate homeostasis.
The endocannabinoid system is part of the nervous system which connects multiple important physiological systems involved in establishing and maintaining animal health.
US Federal Government Patent 6630507 “Cannabinoids as antioxidants and neuroprotectants.”
What is distillation?
Distillation is the process of first heating a mixture to separate the more volatile from the less volatile parts, and then cooling and condensing the resulting vapor so as to produce a more nearly pure or refined substance.
What is Vacuum Distillation?
Vacuum distillation is the process of heating a mixture to separate the more volatile from the less volatile parts, under pressure which is less than atmospheric to reduce the required boiling point, and then cooling and condensing the resulting vapor as to produce a more nearly pure or refined substance.
How do you measure Vacuum?
Vacuum is usually measured as absolute pressure (say millimeters of mercury).
What are the benefits of distillation?
High vacuum systems achieve gentle separation of materials at the lowest possible temperatures. Unlike batch distillation systems, which maintain large volumes of the material at distillation temperatures, short path evaporators expose products to evaporation temperatures only for a brief period (less than one minute) and evaporation occurs as material flows constantly across the evaporator surface.
Short Path Distillation
Short path distillation gets its name from the distance in which the vapor stream is condensed. In this case, the evaporator wall generates the vapors as the feed moves by gravity, while being agitated and distributed evenly, down the evaporator wall. The vapor stream travels a “short path” directly to the condenser which is located within the evaporator chamber. Since the vapor stream is immediately condensed, the short path distillation process precludes the vapor from forming vapor pressure. This allows ultimate pressures of 0.001 mbar to be attained. This also allows heat sensitive materials to undergo purification at much lower temperatures preventing degradation. It allows for very high ambient equivalent temperatures to be achieved. Short path distillation in a plant setting is a continuous process.
The distillation of heat sensitive materials can be complicated; especially when the temperature at which distillation must be performed is high enough to cause thermal decomposition. Although the risk of thermal damage can be greatly reduced by distillation under vacuum, the duration of exposure to even moderate temperatures must also be considered. While, in most cases, the risk of thermal decomposition increases exponentially with temperature, it also increases linearly with the duration of thermal exposure. Short path distillation addresses each of these factors by permitting distillation at the lowest possible pressure with the shortest possible residence time.
What are terpenes?
Terpenes are organic compounds which are actually found in a variety of plants as well as produced by some insects. Terpenes are major biosynthetic building blocks within nearly every living creature.
A more in depth look at terpenes…
Terpenes are a large and diverse class of organic compounds, produced by a variety of plants, particularly conifers, and by some insects such as termites and swallowtail butterflies, which emit terpenes from their osmeteria. They often have a strong odor and may protect the plants that produce them by deterring herbivores and by attracting predators and parasites of herbivores. The difference between terpenes and terpenoids is that terpenes are hydrocarbons, whereas terpenoids contain additional functional groups.
They are the major components of resin. In addition to their roles as end-products in many organisms, terpenes are major biosynthetic building blocks within nearly every living creature.
When terpenes are modified chemically, such as by oxidation or rearrangement of the carbon skeleton, the resulting compounds are generally referred to as terpenoids.
What is a terpenoid?
The terpenoids, sometimes called isoprenoids, are a large and diverse class of naturally occurring organic chemicals similar to terpenes, derived from five-carbon isoprene units assembled and modified in thousands of ways. Most are multicyclic structures that differ from one another not only in functional groups but also in their basic carbon skeletons. These lipids can be found in all classes of living things, and are the largest group of natural products. About 60% of known natural products are terpenoids.
Plant terpenoids are used extensively for their aromatic qualities and play a role in traditional herbal remedies. Terpenoids contribute to the scent of eucalyptus, the flavors of cinnamon, cloves, and ginger, the yellow color in sunflowers, and the red color in tomatoes. Well known terpenoids include citral, menthol, camphor, salvinorin A in the plant Salvia divinorum, the cannabinoids found in cannabis, ginkgolide and bilobalide found in Gingko biloba, and the curcuminoids found in turmeric and mustard seed.
What is the entourage effect?
In short, an entourage effect is when many different cannabinoids, terpenoids, flavonoids etc. contribute to the overall results.
Entourage effect is a phrase that was introduced in cannabinoid science in 1998 by S. Ben-Shabat, with Raphael Mechoulam, to represent a novel endogenous cannabinoid molecular regulation route.
Biological activity assayed together with inactive compounds. References whole plant and whole person caregiver synergy treatments over isolated compound pharmacological dosages. Other cannabinoids, terpenoids and flavonoids contribution to clinical cannabis effects has been espoused as an “entourage effect”
What does it mean to titrate a drug?
Titration is the process of determining the medication dose that reduces symptoms to the greatest possible degree while avoiding possible side effects.
Glossary of Nutritional Terms
Capsaicin – is an active component of chili peppers, which are plants belonging to the genus Capsicum. It is an irritant for mammals, including humans, and produces a sensation of burning in any tissue with which it comes into contact.
Menthol – an organic compound made synthetically or obtained from corn mint, peppermint, or other mint oils. Menthol has local anesthetic and counterirritant qualities, and it is widely used to relieve minor throat irritation. Menthol also acts as a weak kappa opioid receptor agonist.
Camphor – It is a terpenoid found in the wood of the camphor laurel. The oil in rosemary leaves, in the mint family, contains 10 to 20% camphor.
Antipruritic – also known as anti-itch drugs, are medications that inhibit the itching (Latin: pruritus) often associated with sunburns, allergic reactions, eczema, psoriasis, chickenpox, fungal infections, insect bites and stings like those from mosquitoes, fleas, and mites, and contact dermatitis and urticaria caused by plants such as poison ivy (urushiol-induced contact dermatitis) or stinging nettle.
Analgesic – or painkiller is any member of the group of drugs used to achieve analgesia, relief from pain. Analgesic drugs act in various ways on the peripheral and central nervous systems.
Counterirritant – is a substance which creates irritation or mild inflammation in one location with the goal of lessening discomfort and/or inflammation in another location. This strategy falls into the more general category of counterstimulation.
Thermosensation – or thermoreception is the sense by which an organism perceives temperature, or more accurately, temperature differences inferred from heat flux. Transient receptor potential channels (TRP channels) are believed to play a role in many species in sensation of hot, cold, and pain. Mammals have at least two types of sensor: those that detect heat (i.e., temperatures above body temperature) and those that detect cold (i.e. temperatures below body temperature).
Mechanosensation – is a response mechanism to mechanical stimuli. The physiological foundation for the senses of touch, hearing and balance, and pain is the conversion of mechanical stimuli into neural signals: mechanosensation.
Pheromone – is a secreted or excreted chemical factor that triggers a social response in members of the same species. Pheromones are chemicals capable of acting like hormones outside the body of the secreting individual, to impact the behavior of the receiving individuals. – These chemical messengers are transported outside of the body and affect neural circuits, including the autonomic nervous system with hormone or cytokine mediated physiological changes, inflammatory signaling, immune system changes and/or behavioral change in the recipient.
Quorum sensing – is the ability to detect and to respond to cell population density by gene regulation. As one example, quorum sensing (QS) enables bacteria to restrict the expression of specific genes to the high cell densities at which the resulting phenotypes will be most beneficial. Many species of bacteria use quorum sensing to coordinate gene expression according to the density of their local population.
Gustation – Taste, gustatory perception, or gustation is one of the five traditional senses that belongs to the gustatory system. Taste is the sensation produced when a substance in the mouth reacts chemically with taste receptor cells located on taste buds in the oral cavity, mostly on the tongue.
Nociceptive sensory neurons – A nociceptor is a sensory neuron that responds to damaging or potentially damaging stimuli by sending “possible threat” signals to the spinal cord and the brain. If the brain perceives the threat as credible, it creates the sensation of pain to direct attention to the body part, so the threat can hopefully be mitigated; this process is called nociception.
Chemosensitive – A chemosensitivity assay is a laboratory test that measures the number of tumor cells that are killed by chemotherapy. The test is done after the tumor cells are removed from the body. A chemosensitivity assay may help in choosing the best drug or drugs for the cancer being treated.
Acute desensitization – In medicine, desensitization is a method to reduce or eliminate an organism’s negative reaction to a substance or stimulus. In pharmacology, drug desensitization is equivalent to drug tolerance, though the latter term refers to the more general concept of subjects’ reactions (positive or negative) to a drug reducing following its repeated use.
Tachyphylaxis – is a medical term describing an acute, sudden decrease in response to a drug after its administration, i.e. a rapid and short-term onset of drug tolerance. It can occur after an initial dose or after a series of small doses. Increasing the dose of the drug may be able to restore the original response.
Dorsal root ganglion neurons – (or spinal ganglion) (also known as a posterior root ganglion), is a cluster of neurons (a ganglion) in a dorsal root of a spinal nerve. The cell bodies of sensory neurons known as first-order neurons are located in the dorsal root ganglia. The nerve endings of dorsal root ganglion neurons have a variety of sensory receptors that are activated by mechanical, thermal, chemical, and noxious stimuli.
Keratinocytes – is the predominant cell type in the epidermis, the outermost layer of the skin, constituting 90% of the cells found there. Those keratinocytes found in the basal layer (stratum basale) of the skin are sometimes referred to as “basal cells” or “basal keratinocytes”. The primary function of keratinocytes is the formation of a barrier against environmental damage by pathogenic bacteria, fungi, parasites, viruses, heat, UV radiation and water loss. Once pathogens start to invade the upper layers of the epidermis, keratinocytes can react by producing proinflammatory mediators, particularly chemokines such as CXCL10 and CCL2 which attract leukocytes to the site of pathogen invasion.
Mustard oil activates TRPA1 – The term mustard oil is used for two different oils that are made from mustard seeds:
A fatty vegetable oil resulting from pressing the seeds and an essential oil resulting from grinding the seeds, mixing them with water, and extracting the resulting volatile oil by distillation.
The pungency of mustard oil is due to the presence of allyl isothiocyanate, an activator of the TRPA1 channel.
Allyl isothiocyanate – is the organosulfur compound with the formula CH2CHCH2NCS. This colorless oil is responsible for the pungent taste of mustard, radish, horseradish, and wasabi. This pungency and the lachrymatory effect of AITC are mediated through the TRPA1 and TRPV1 ion channels. It is slightly soluble in water, but more soluble in most organic solvents.
TRPA1 – Transient receptor potential cation channel, subfamily A, member 1, also known as transient receptor potential ankyrin 1 or TRPA1, is a protein that in humans is encoded by the TRPA1. TRPA1 is an ion channel located on the plasma membrane of many human and animal cells. This ion channel is best known as a sensor for environmental irritants giving rise to somatosensory modalities such as pain, cold and itch.
TRPV1 – The transient receptor potential cation channel subfamily V member 1 (TrpV1), also known as the capsaicin receptor and the vanilloid receptor 1, is a protein that, in humans, is encoded by the TRPV1 gene. It was the first isolated member of the transient receptor potential vanilloid receptor proteins that in turn are a sub-family of the transient receptor potential protein group. This protein is a member of the TRPV group of transient receptor potential family of ion channels. The function of TRPV1 is detection and regulation of body temperature. In addition, TRPV1 provides a sensation of scalding heat and pain (nociception).
CBD Resources & Position Statements
ProjectCBD.org has a great deal of information on Cannabidiol
Epilepsy Foundation, The Epilepsy Foundation’s CBD Position & Statement + Additional Resources on Medical Marijuana and CBD Research and Journal Articles
American Nurses Association’s (ANA), Position statement on Therapeutic Use of Marijuana and Related Cannabinoids [PDF]
American Cannabis Nurses Association (ACNA), ACNA position statements
Celebrities who have talked about CBD:
|Sanjay Gupta, MD||Whoopie Goldberg|
|Morgan Freeman||Montel Williams|
|Tommy Chong||Nate Diaz (video)|
|Melissa Etheridge||Dr. Oz|
Please review the FDA & consumer safety information below.
Professional CBD Education - CNE & CME
CBD Education for Medical Professionals
CBD Houston, LLC does not provide medical products, however, we’re often asked about professional educational resources and continuing education resources on the topics of CBD, cannabis, and medical marijuana.
Accredited Continuing Nursing Education (CNE)
Medical Cannabis Curriculum for Nurses
WHO: American Cannabis Nurses Association (ACNA) and The Medical Cannabis Institute (TMCI)
WHAT: 8 Continuing Nursing Education (CNE) hours – online CNE
APPROVAL: approved by the Virginia Nurses Association, an accredited approver by the American Nurses Credentialing Center’s Commission on Accreditation.
Accredited Continuing Medical Education (CME)
WHO: The University of Vermont, Larner College of Medicine
WHAT: “5 online modules with 1-2 hours of content focused on Cannabis for therapeutic use” – online CME
FDA Disclosure and Consumer Information
This website, CBD Houston LCC, and its representatives do not provide medical advice.
We always suggest consulting with your doctor, medical, or wellness practitioner.
CBD Houston LLC’s products are not intended to diagnose, treat, cure, or prevent any disease.
The information on this website has not been evaluated by the FDA, and is not intended to diagnose, treat, prevent, or cure any disease.
Additional Consumer Information
Be wary of products or businesses who make health claims about or who claim that their CBD oil or CBD products are FDA approved.
Select quotes from the FDA’s website post entitled “Is it Really FDA Approved?”
- FDA doesn’t approve companies.
- FDA doesn’t approve medical foods.
- FDA doesn’t approve dietary supplements.
- FDA does not “approve” … laboratories, or manufacturers. FDA does have authority to inspect regulated facilities to verify that they comply with applicable good manufacturing practice regulations.
Material to Consider
Warning Letters and Test Results for Cannabidiol-Related Products
FDA warns companies marketing unproven products, derived from marijuana, that claim to treat or cure cancer
Is It Really ‘FDA Approved?’ – Page Accessed: 09/27/2017
Drug Approvals and Databases – National Drug Code Directory – Page Accessed: 09/27/2017